Endocrine Abstracts

Introduction: Optimal anti-thyroid regimen for management of Graves’ disease is still a matter of controversy. The aim of this study is determination of remission rate and long-term relapse rate after low-dose anti-thyroid drug therapy.Method: This study is a long-term retrospective study. We selected 100 patients with the diagnosis of Graves’ disease that admitted to our endocrinology clinic from January 2000 until December 2010. All of patien...

Background: There are remarkable debates on the pathogenic mechanisms of Graves’ disease (GD). We prospectively followed up the serum levels of different autoimmunity indices in patients with GD in order to elucidate their pattern of alteration with time.Methods: A total of 119 consecutive patients with GD were treated using low dose anti-thyroid medications at the initial dose of 20 mg/day of methimazole (MMI). Then, the dose was gradually decrease...